Increased gait variability in diabetes mellitus patients with neuropathic pain
| Autor: | Ayechen Chan, Cory Toth, Alexandra Garven, Paul Lalli, E. W. Block, Nisha Midha, Cynthia Chan, Bin Hu, Shauna Brady |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Diabetic neuropathy Endocrinology Diabetes and Metabolism Monitoring Ambulatory Walking Fear of falling Severity of Illness Index Alberta Cohort Studies Endocrinology Physical medicine and rehabilitation Risk Factors Diabetes mellitus Internal Medicine medicine Humans Diabetic Nephropathies Gait Disorders Neurologic Aged Retrospective Studies Glycated Hemoglobin business.industry Type 2 Diabetes Mellitus Middle Aged medicine.disease Gait Hospitalization Peripheral neuropathy Cross-Sectional Studies Neuropathic pain Cohort Physical therapy Neuralgia Wounds and Injuries Accidental Falls Female medicine.symptom business |
| Zdroj: | Journal of diabetes and its complications. 27(3) |
| ISSN: | 1873-460X |
| Popis: | Aims Gait dysfunction in subjects with diabetes mellitus (DM) contributes to falling and subsequent injuries. Using a portable device (GaitMeter™), we measured gait parameters in DM patients with and without diabetic peripheral neuropathy (DPN) during flat surface walking. We hypothesized that DM patients with DPN and neuropathic pain (NeP) would have greater gait step variability than those with DPN without NeP. Methods Subjects with DPN and at least moderate NeP (DPN-P), DPN without NeP (DPN-NoP), DM without DPN, and control subjects without DM were assessed. Our outcome measure was gait variability for step length and velocity. DPN severity was quantified using the Toronto Clinical Scoring System and the Utah Early Neuropathy Score. Falls and their outcomes were retrospectively quantified. Results Each cohort contained≥20 subjects. Durations of DM and HbA1C were greatest amongst DPN cohorts. DPN-P participants had greater variability of step length and step velocity, except for DM only participants. DPN-P participants also reported greater risk of hospitalizations for fall-related injuries, and greater fear of falling. Modest negative relationships emerged for step length with step velocity, reported falls and pain severity. Conclusions NeP contributes to gait variability, potentially contributing to the risk of falling in DM patients. |
| Databáze: | OpenAIRE |
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