Additional file 1 of Comparison of ELISA- and SIMOA-based quantification of plasma Aβ ratios for early detection of cerebral amyloidosis

Autor: Meyer, Steffi De, Schaeverbeke, Jolien M., Verberk, Inge M. W., Gille, Benjamin, Schaepdryver, Maxim De, Luckett, Emma S., Gabel, Silvy, Bruffaerts, Rose, Mauroo, Kimberley, Thijssen, Elisabeth H., Stoops, Erik, Vanderstichele, Hugo M., Teunissen, Charlotte E., Vandenberghe, Rik, Poesen, Koen
Rok vydání: 2020
Předmět:
DOI: 10.6084/m9.figshare.13337729
Popis: Additional file 1: Appendix 1. Conversion of [18F]flutemetamol and [18F]florbetaben SUVR to the Centiloid scale. Supplementary Table 1. Plasma amyloid and tau performance (AUC) differences between platforms and subgroups for detecting amyloid-PET positivity. Supplementary Table 2. Performance of adjusted biomarker models relative to a basic demographic model and unadjusted biomarker models Supplementary Table 3. Sensitivities, specificities, PPVs and NPVs of logistic regression models corrected for age and APOE-ε4 genotype. Supplementary Figure 1. Comparison of ELISA and SIMOA measurements of plasma Aβ1-42/Aβ1-40 and Aβ1-42/t-tau. Supplementary Figure 2. ROC curves of plasma amyloid and tau with amyloid-PET as the standard-of-truth. Supplementary Figure 3. Correlations of ELISA and SIMOA plasma amyloid and tau levels with Centiloids and CSF Aβ1-42/t-tau.
Databáze: OpenAIRE