A phenacrylate scaffold for tunable thiol activation and release
| Autor: | Harinath Chakrapani, Rathinam K. Sankar, Allimuthu T. Dharmaraja, Rohan Kumbhare |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
chemistry.chemical_classification
Scaffold Fluorophore Coumaric Acids Cell Survival Metals and Alloys Nanotechnology General Chemistry Decomposition Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound Acrylates chemistry Materials Chemistry Ceramics and Composites Thiol Biophysics Humans Sulfhydryl Compounds Fluorescent Dyes HeLa Cells |
| Zdroj: | Chem. Commun.. 50:15323-15326 |
| ISSN: | 1364-548X 1359-7345 |
| Popis: | A thiol-selective 2-methyl-3-phenacrylate scaffold with spatiotemporal control over delivery of a cargo is reported. The half-lives of decomposition could be tuned from 30 min to 1 day and the scaffold's utility in thiol-inducible fluorophore release in cell-free as well as within cells is demonstrated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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