Internal Mammary Sentinel Lymph Node Biopsy With Modified Injection Technique

Autor: Binbin Cong, Rong-Rong Zhao, Peng-Fei Qiu, Yan-Bing Liu, Guo-Ren Yang, Peng Chen, Yong-Sheng Wang
Rok vydání: 2015
Předmět:
Zdroj: Medicine
ISSN: 0025-7974
DOI: 10.1097/md.0000000000001790
Popis: Although the 2009 American Joint Committee on Cancer incorporated the internal mammary sentinel lymph node biopsy (IM-SLNB) concept, there has been little change in surgical practice patterns because of the low visualization rate of internal mammary sentinel lymph nodes (IMSLN) with the traditional radiotracer injection technique. In this study, various injection techniques were evaluated in term of the IMSLN visualization rate, and the impact of IM-SLNB on the diagnostic and prognostic value were analyzed. Clinically, axillary lymph nodes (ALN) negative patients (n = 407) were divided into group A (traditional peritumoral intraparenchymal injection) and group B (modified periareolar intraparenchymal injection). Group B was then separated into group B1 (low volume) and group B2 (high volume) according to the injection volume. Clinically, ALN-positive patients (n = 63) were managed as group B2. Internal mammary sentinel lymph node biopsy was performed for patients with IMSLN visualized. The IMSLN visualization rate was significantly higher in group B than that in group A (71.1% versus 15.5%, P
Databáze: OpenAIRE