| Autor: |
Wang, Biao, He, Bang-Shun, Ruan, Xiao-Lan, Zhu, Jiang, Hu, Rui, Wang, Jie, Li, Ying, Yang, Yun-Huang, Liu, Mai-Li |
| Rok vydání: |
2022 |
| DOI: |
10.6084/m9.figshare.21184249 |
| Popis: |
Additional file 1: Fig. S1. Design and simulation of the microfluidic device. Fig. S2. Overall pattern of the fabricated microfluidic device (a) and fabricated microchamber array (b). Fig. S3. Single cell array formed in the single-plexed device and the single-cell derived clones in a typical experiment. Fig. S4. Evaluation of on-chip cell proliferation. Fig. S5. Characterization of the on-chip concentration gradient generation. Fig. S6. Images of the single K562 cell array after the treatment of Imatinib (a) or Resveratrol (b) for 24 h on the microfluidic device. Fig. S7. Single drug treatment (Imatinib) of single K562 cell derived clones. Fig. S8. Single drug treatment (Resveratrol) to single K562 cell derived clones. Fig. S9. Separation of CD34+ acute myeloid leukemia cells from patient bone marrow species. Fig. S10. Optimized microchamber array for primary cell capture. Fig. S11. Evaluation of the concentration gradient generation on the modified device with fluorescein sodium (green) and sulforhodamine B (red) under 0.05 μl/min. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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