Minority Veterans Are More Willing to Participate in Complex Studies Compared to Non-minorities
| Autor: | Irene Kirolos, Ana Palacio, Erin N. Marcus, Jimmy Rivadeneira, Fiorella Pendola, Leonardo Tamariz, Olveen Carrasquillo |
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| Rok vydání: | 2016 |
| Předmět: |
Therapeutic Misconception
medicine.medical_specialty Health (social science) Population Health literacy Medical law 0603 philosophy ethics and religion 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires medicine Odds Ratio Humans 030212 general & internal medicine education Minority Groups Aged Veterans education.field_of_study Insurance Health Therapeutic misconception business.industry Health Policy Clinical study design Patient Selection Research 06 humanities and the arts Odds ratio Middle Aged Health Literacy Clinical trial Clinical research Attitude Family medicine Hypertension 060301 applied ethics business |
| Zdroj: | Journal of bioethical inquiry. 15(1) |
| ISSN: | 1176-7529 |
| Popis: | Minorities are an underrepresented population in clinical trials. A potential explanation for this underrepresentation could be lack of willingness to participate. The aim of our study was to evaluate willingness to participate in different hypothetical clinical research scenarios and to evaluate the role that predictors (e.g. health literacy) could have on the willingness of minorities to participate in clinical research studies. We conducted a mixed-methods study at the Miami VA Healthcare system and included primary care patients with hypertension. We measured willingness to participate as a survey of four clinical research scenarios that evaluated common study designs encountered in clinical research and that differed in degree of complexity. Our qualitative portion included comments about the scenarios. We included 123 patients with hypertension in our study. Of the entire sample, ninety-three patients were minorities. Seventy per cent of the minorities were willing to participate, compared to 60 per cent of the non-minorities. The odds ratio (OR) of willingness to participate in simple studies was 0.58; 95 per cent CI 0.18–1.88 p=0.37 and the OR of willingness to participate in complex studies was 5.8; 95 per cent CI 1.10–1.31 p=0.03. In complex studies, minorities with low health literacy cited obtaining benefits (47 per cent) as the most common reason to be willing to participate. Minorities who were not willing to participate, cited fear of unintended outcomes as the main reason. Minorities were more likely to be willing to participate in complex studies compared to non-minorities. Low health literacy and therapeutic misconception are important mediators when considering willingness to participate in clinical research. |
| Databáze: | OpenAIRE |
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