Prognostic value of respiratory quotients in severe polytrauma patients with nutritional support
| Autor: | Eduard Havel, Miroslav Kovarik, Miloslav Hronek, A. Patkova, Zdenek Zadak, Simona Najpaverova, Daniela Uramova, Vera Joskova |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 0301 basic medicine Parenteral Nutrition medicine.medical_specialty Time Factors Endocrinology Diabetes and Metabolism medicine.medical_treatment Energy metabolism Pilot Projects law.invention 03 medical and health sciences law medicine Humans Resting energy expenditure Prospective Studies Respiratory system Intensive care medicine Mechanical ventilation 030109 nutrition & dietetics Nutrition and Dietetics Multiple Trauma business.industry Calorimetry Indirect Fasting Length of Stay Middle Aged Prognosis medicine.disease Respiration Artificial Polytrauma Intensive care unit Respiratory Function Tests Respiratory quotient Intensive Care Units Treatment Outcome Parenteral nutrition Emergency medicine Regression Analysis Female Basal Metabolism Energy Metabolism business |
| Zdroj: | Nutrition. 49:90-95 |
| ISSN: | 0899-9007 |
| DOI: | 10.1016/j.nut.2017.10.013 |
| Popis: | The association between energy metabolism and prognosis in polytrauma patients has not yet been defined. The aim of this study was to describe energy metabolism and analyze the prognostic value of respiratory quotient (RQ) and nonprotein respiratory quotient (npRQ) in fasting polytrauma patients (fPP) and polytrauma patients with nutritional support (nsPP).Twenty-two polytrauma patients (before and after parenteral nutrition administration) and 22 healthy controls (after overnight fasting) were examined on day 4 (median) after admission to the intensive care unit. To evaluate energy expenditure in nsPP and resting energy expenditure in fPP and controls with RQ and npRQ in all groups, we used indirect calorimetry. With regression analysis, the descriptive models of intensive care unit (ICU) length of stay (LOS) and mechanical ventilation time (VT) were derived.RQ and npRQ were significantly lower in fPP than in controls (P 0.05 and P 0.01, respectively) and in nsPP (P 0.05). In nsPP, relationships between RQ or npRQ and the ICU LOS or mechanical VT were demonstrated (P 0.0001, r = -0.78 for RQ and VT; P 0.0001, r = -0.78 for npRQ and VT; P 0.001, r = -0.69 for RQ and LOS; P 0.001, r = -0.72 for npRQ and LOS).RQ and npRQ parameters measured by indirect calorimetry in polytrauma patients with parenteral nutrition on the fourth day of ICU stay related to clinical outcomes such as duration of mechanical ventilation and ICU LOS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect