Pitfalls in Diagnosing Brain Death in Infancy
| Autor: | Gilbert J. Toffol, Romulo E. Ortega, Walter S. Tan, John R. Hughes, Susan A. Kecskes, Michael J. Blend, Dan G. Pavel, Lester L. Lansky |
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| Rok vydání: | 1987 |
| Předmět: |
Male
Nervous system Brain Death Central nervous system Trisomy Context (language use) 030204 cardiovascular system & hematology Electroencephalography 03 medical and health sciences 0302 clinical medicine Basal ganglia Humans Medicine 030212 general & internal medicine Evoked Potentials medicine.diagnostic_test business.industry Sugar Acids Technetium Organotechnetium Compounds Blood flow medicine.disease Heart Arrest medicine.anatomical_structure Cerebral blood flow Cerebrovascular Circulation Child Preschool Anesthesia Pediatrics Perinatology and Child Health Neurology (clinical) Chromosomes Human Pair 18 business |
| Zdroj: | Journal of Child Neurology. 2:134-138 |
| ISSN: | 1708-8283 0883-0738 |
| DOI: | 10.1177/088307388700200209 |
| Popis: | A 3-year-old child with phenotypic trisomy 18 syndrome survived 26 days after a cardiopulmonary arrest, secondary to an acute viral illness. The child was deeply comatose. No barbiturates, other sedatives, or aminoglycoside antibiotics had been recently administered. The child was normothermic with adequate cardiovascular function. Brain stem function was absent, as assessed by testing of brain stem reflexes. Serial cerebral radionuclide angiograms (CRAG) documented intact cerebral blood flow while electrocerebral silence (ECS) was present on two consecutive EEG recordings within 24 hours. Preservation of intracranial circulation was confirmed by rapid rotational computed tomographic (CT) scans. Cranial CT scans also revealed communicating hydrocephalus, and bilateral basal ganglia hemorrhages. This unusual case illustrates discordance between apparent irreversible loss of cortical function as indicated by electrocerebral silence with preserved cerebral blood flow. The implications of these apparent paradoxical events will be discussed in the context of defining brain death in children. ( J Child Neurol 1987;2:134-138). |
| Databáze: | OpenAIRE |
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