Comparison of agarose and cross-linked protein gels as magnetic resonance imaging phantoms
| Autor: | Scott D. Kennedy, Cathy Coolbaugh Lester, Lidia S. Szczepaniak, Janice Filion Heinsbergen, Daniel A. Mendelson, Robert G. Bryant |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Physics::Medical Physics
Biomedical Engineering Biophysics Imaging phantom chemistry.chemical_compound Paramagnetism Nuclear magnetic resonance medicine Animals Radiology Nuclear Medicine and imaging Magnetization transfer Bovine serum albumin Quantitative Biology::Biomolecules medicine.diagnostic_test biology Chemistry Sepharose Relaxation (NMR) Magnetic resonance imaging Serum Albumin Bovine equipment and supplies Magnetic Resonance Imaging Magnetic field Rats Models Structural biology.protein Agarose Cattle Female Gels |
| Zdroj: | Magnetic resonance imaging. 9(6) |
| ISSN: | 0730-725X |
| Popis: | Measurements of the magnetic field dependence of spin-lattice relaxation rates and the response of the water-proton signal intensity to off-resonance radio frequency fields show that the commonly used agarose phantom provides a less faithful representation for the magnetic response of tissue than does a cross-linked protein system. The origin of these differences lies in the structure and intramolecular dynamics of the macromolecular system used to make the gel. These distinctions will also cause differences in the magnetic response of the water spin system when paramagnetic relaxation agents or contrast agents are incorporated. Use of a thermally cross-linked bovine serum albumin phantom is suggested. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|