Body mass index and lung cancer risk: results from the ICARE study, a large, population-based case-control study
| Autor: | Anne Sophie Woronoff, Loredana Radoï, Florence Guida, Sylvie Cénée, Sophie Paget-Bailly, Isabelle Stücker, Annie Schmaus, Gwenn Menvielle, Alexandra Papadopoulos, Diane Cyr, Chloé Tarnaud, A. Buemi, Danièle Luce |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Chronic bronchitis Lung Neoplasms Population Risk Assessment Body Mass Index Risk Factors Internal medicine medicine Humans Lung cancer education Aged education.field_of_study business.industry Weight change Body Weight Smoking Case-control study Odds ratio Middle Aged medicine.disease Confidence interval Surgery Logistic Models Oncology Case-Control Studies Population Surveillance Female France business Body mass index |
| Zdroj: | Cancer causescontrol : CCC. 23(7) |
| ISSN: | 1573-7225 |
| Popis: | The association between body mass index (BMI) and lung cancer is still disputed because of possible residual confounding by smoking and preclinical weight loss in case–control studies. We examined this association using data from the multicenter ICARE study in France, a large, population-based case–control study. A total of 2,625 incident lung cancer cases and 3,381 controls were included. Weight was collected at interview, 2 years before the interview, and at age 30. Lifetime smoking exposure was calculated using the comprehensive smoking index (CSI). Adjusted odds ratios (aORs) and 95 % confidence intervals were estimated by unconditional logistic regression and controlled for age, area, education, CSI, occupational exposure, previous chronic bronchitis, and parental history of lung cancer. We also examined the role of weight change. Analyses were stratified by smoking status and sex. When compared with that of men with normal BMI 2 years before the interview, lung cancer aORs (95 % CI) among men with BMIs of |
| Databáze: | OpenAIRE |
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