The specificity and sensitivity of CSF and blood glucose concentration in the diagnosis of neonatal meningitis
| Autor: | J.A. Omene, A. C. Longe, D N Onyia, A.A. Okolo |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Pediatrics CSF glucose 030231 tropical medicine Gastroenterology Neonatal meningitis 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid 030225 pediatrics Internal medicine medicine Humans Meningitis Prospective Studies Risk factor Prospective cohort study biology business.industry Infant Newborn Bacterial Infections medicine.disease biology.organism_classification Glucose Tasa Pediatrics Perinatology and Child Health Bacterial meningitis business |
| Zdroj: | Annals of Tropical Paediatrics. 5:37-39 |
| ISSN: | 1465-3281 0272-4936 |
| DOI: | 10.1080/02724936.1985.11748357 |
| Popis: | In a prospective study of high-risk newborn infants, the specificity and sensitivity of CSF/blood glucose ratio were studied in 35 newborn infants with meningitis and 100 high-risk neonates without meningitis. High CSF/blood glucose ratios of 0.93 (0.17) (Mean (S.D.) ) for preterm infants and 0.96 (0.30) (Mean (S.D.) ) for term infants were observed. The CSF/blood glucose ratios of less than 0.6 for preterm meningitic and less than 0.5 for term meningitic infants had the highest specificity (100%). The corresponding sensitivity of these ratios in the diagnosis of meningitis was 74.3% and 71.4% respectively. Similarly, an absolute CSF glucose value of less than 1.3 mmol/l in infants with meningitis was highly specific. Nevertheless, complete clinical evaluation of the infant is important if bacterial meningitis is suspected and the decision to treat should not be based on CSF glucose findings alone. |
| Databáze: | OpenAIRE |
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