Molecular diagnostics: harmonization through reference materials, documentary standards and proficiency testing
| Autor: | Marcia J. Holden, Lisa V. Kalman, Roberta M Madej, Philip D. Minor |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Quality Control
Laboratory Proficiency Testing business.industry Genetic Diseases Inborn MEDLINE Harmonization Documentation Reference Standards Nucleic Acid Testing Molecular diagnostics Bioinformatics Communicable Diseases Pathology and Forensic Medicine Molecular Diagnostic Techniques External quality assessment Genetics Proficiency testing Humans Molecular Medicine Medicine Engineering ethics business Molecular Biology Reference standards |
| Zdroj: | Expert Review of Molecular Diagnostics. 11:741-755 |
| ISSN: | 1744-8352 1473-7159 |
| Popis: | There is a great need for harmonization in nucleic acid testing for infectious disease and clinical genetics. The proliferation of assay methods, the number of targets for molecular diagnostics and the absence of standard reference materials contribute to variability in test results among laboratories. This article provides a comprehensive overview of reference materials, related documentary standards and proficiency testing programs. The article explores the relationships among these resources and provides necessary information for people practicing in this area that is not taught in formal courses and frequently is obtained on an ad hoc basis. The aim of this article is to provide helpful tools for molecular diagnostic laboratories. |
| Databáze: | OpenAIRE |
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