Letter to the editor concerning the article 'Safety of vaccines administration in hereditary fructose intolerance'
| Autor: | Rosaura Leis, Vanesa Crujeiras-Martinez, Nazareth Martinón-Torres, María L. Couce, Rebeca Saborido-Fiaño |
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| Rok vydání: | 2021 |
| Předmět: |
Rotavirus
medicine.medical_specialty Letter to the editor Sucrose Letter Hereditary fructose intolerance 030231 tropical medicine Immunology Vaccines Attenuated Rotavirus Infections 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Immunology and Allergy Humans 030212 general & internal medicine Letters Pharmacology business.industry Vaccination Rotavirus Vaccines Infant Fructose medicine.disease Fructose Intolerance Endocrinology chemistry Italy Sorbitol business |
| Zdroj: | Hum Vaccin Immunother |
| ISSN: | 2164-554X |
| Popis: | The most important approach for the management of hereditary fructose intolerance is a strict avoidance of fructose, sucrose and sorbitol from the diet and medications. A safe threshold of 2.4 mg/kg/dose was recently established by the Instituto Superiore di Sanità of Italy for both oral and parenteral routes, thus shouldering a safe administration of a majority of vaccines in these patients. This would not include, Rotarix® pre-established oral suspension and Rotateq® vaccines, which are indeed contraindicated. Moreover, Rotarix® white powder and solvent for oral suspension would only be safely administered at a weight above 9.3 kg. Overall, these recommendations to avoid rotavirus vaccination are difficult to implement because these vaccines are given during exclusive breastfeeding, prior to fructose-containing food introduction. |
| Databáze: | OpenAIRE |
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