Androgen insufficiency in women: diagnostic and therapeutic implications
| Autor: | Henry G. Burger, Susan R. Davis, Mary-Anne Papalia, Livia Rivera-Woll |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
Pediatrics Reduced libido Hormone Replacement Therapy Mood Disorders business.industry Libido Obstetrics and Gynecology Testosterone (patch) Syndrome Testosterone level Endocrinology Mood Reproductive Medicine Serum free Internal medicine Androgens medicine Hormone replacement therapy (male-to-female) Animals Female Testosterone replacement Androgen insufficiency business |
| Zdroj: | Human Reproduction Update. 10:421-432 |
| ISSN: | 1460-2369 1355-4786 |
| Popis: | The proposed key symptoms of the female androgen insufficiency syndrome (FAIS) include reduced libido, diminished well being and lowered mood. The diagnosis of FAIS is made on the basis of these symptoms in the setting of a low serum free testosterone level. However, there is currently no readily available inexpensive assay which reliably measures free testosterone levels in the female range. The diagnosis of FAIS is further complicated by the lack of data demonstrating a minimum serum free testosterone level which, if below this, correlates with the symptoms of FAIS. Despite the complexities involved with defining FAIS, the symptoms have been reported to respond well to testosterone replacement. There is a need for formulations of testosterone therapy specifically designed for use in women, along with clear guidelines regarding optimal therapeutic doses and long-term safety data. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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