Previous respiratory tract infections and antibiotic consumption in children with long- and short-term carriage of penicillin-resistant Streptococcus pneumoniae
| Autor: | K. Ekdahl, O. Gunnarsson |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Time Factors Epidemiology medicine.drug_class Acute otitis media Penicillin Resistance Antibiotics Penicillin resistant Streptococcus pneumoniae Risk Factors Internal medicine medicine Humans Child Respiratory Tract Infections Respiratory tract infections business.industry Age Factors Infant Host defence Anti-Bacterial Agents Streptococcus pneumoniae Infectious Diseases medicine.anatomical_structure Carriage Child Preschool Carrier State Immunology business Research Article Respiratory tract |
| Zdroj: | Epidemiology and Infection. 121:523-528 |
| ISSN: | 1469-4409 0950-2688 |
| DOI: | 10.1017/s0950268898001599 |
| Popis: | Previous respiratory tract infections (RTI) and antibiotics consumption as possible risk factors for extended duration of PRP carriage were investigated in 24 children (cases) with previous carriage of penicillin-resistant pneumococci (PRP) for a duration exceeding 120 days (median 168 days) and a control group of 53 children with a duration of PRP carriage less than 90 days (median 21 days). The cases had experienced 0·99 episodes of acute otitis media (AOM) per life-year compared to 0·79 episodes in the controls (P=0·32). For antibiotic-treated RTI other than AOM, the corresponding numbers were 0·49 and 0·29 episodes per life-year, respectively (P=0·01). No differences in antibiotic consumption in the 3 months preceding the carriage, nor during the carriage period were noted. Other factors than impaired host defence to respiratory tract pathogens or antibiotics consumption seem to be more important in determining the duration of PRP carriage. |
| Databáze: | OpenAIRE |
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