Effects of the probiotic Bifidobacterium animalis subsp. lactis on the non-surgical treatment of periodontitis. A histomorphometric, microtomographic and immunohistochemical study in rats
| Autor: | Luiz F.F. Oliveira, Cristina Stewart Bittencourt Bogsan, Flávia A.C. Furlaneto, Maricê Nogueira de Oliveira, Michel Reis Messora, Andre L. Moreira, Milla Sprone Tavares Ricoldi, Gustavo Corrêa de Almeida Teixeira, Edilson Ervolino, Jéssica P. Pischiotini, Sérgio Luiz de Souza Salvador |
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| Přispěvatelé: | Universidade de São Paulo (USP), Private Practice, Universidade Estadual Paulista (Unesp) |
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine lcsh:Medicine environment and public health law.invention Probiotic 0302 clinical medicine Scaling and root planing Oral Diseases law Lactobacillus Medicine and Health Sciences lcsh:Science Musculoskeletal System Colony-forming unit Multidisciplinary biology Genomics Immunohistochemistry Resorption Bifidobacterium animalis Medical Microbiology Anaerobic bacteria Anatomy Immunohistochemical Analysis Research Article Duodenum Oral Medicine Microbial Genomics Anaerobic Bacteria Research and Analysis Methods Microbiology Andrology 03 medical and health sciences LACTOBACILLUS Genetics medicine Animals Rats Wistar Periodontitis Immunohistochemistry Techniques Skeleton Periodontal Diseases Bacteria business.industry Probiotics Skull Gut Bacteria lcsh:R Organisms Biology and Life Sciences X-Ray Microtomography 030206 dentistry medicine.disease biology.organism_classification Rats Histochemistry and Cytochemistry Techniques Gastrointestinal Tract Disease Models Animal 030104 developmental biology Immunologic Techniques Alveolar Bone lcsh:Q Microbiome Bifidobacterium business Digestive System |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP PLoS ONE, Vol 12, Iss 6, p e0179946 (2017) Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP PLoS ONE |
| Popis: | Made available in DSpace on 2018-12-11T17:13:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-06-01 Lactobacillus probiotics have been investigated in periodontitis. However, the effects of the genus Bifidobacterium on periodontitis are hardly known. This study evaluated the effects of the probiotic (PROB) Bifidobacterium animalis subsp. lactis (B. lactis) HN019 as an adjunct to scaling and root planing (SRP) in rats with experimental periodontitis (EP). At baseline, 32 rats were assigned to 4 groups: C (control), PROB, EP-SRP and EP-SRP-PROB. In groups EP-SRP and EP-SRP-PROB, the mandibular first molars of the animals received a ligature. At day 14, the ligatures were removed and SRP was performed. Animals of groups PROB and EP-SRP-PROB were orally administered with 10 mL/day of 109 colony forming units of B. lactis HN019 for 15 days, starting at day 14. Animals were euthanized at day 29. Histomorphometric, microtomographic and immunohistochemical analyses were performed. Microbiological effects of B. lactis on biofilm were also evaluated. Data were statistically analyzed (ANOVA, Tukey; Kruskal-Wallis, Dunn's; Two-tailed t-test; p |
| Databáze: | OpenAIRE |
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