Foveal avascular zone area measurements using OCT angiography in patients with type 2 diabetes mellitus associated with essential hypertension
| Autor: | Ana Raluca Mihalcea, Abdallah Aqel, Sînziana Istrate, Irena Gabriela Paşca, Cecilia Eniceicu, Vasile Potop, Radu Ciuluvica, Daniela Stana, Dana Moraru |
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| Rok vydání: | 2019 |
| Předmět: |
Fovea Centralis
medicine.medical_specialty hypertension genetic structures Fundus Oculi Blood Pressure foveal avascular zone Retinography Essential hypertension Neovascularization Ophthalmology Diabetes mellitus medicine Intraretinal microvascular abnormalities Humans Prospective Studies Fluorescein Angiography Diabetic Retinopathy diabetes business.industry Retinal Vessels General Medicine Diabetic retinopathy medicine.disease eye diseases Blood pressure Diabetes Mellitus Type 2 sense organs Essential Hypertension medicine.symptom General Articles business Tomography Optical Coherence Follow-Up Studies Retinopathy |
| Zdroj: | Romanian Journal of Ophthalmology |
| ISSN: | 2501-2533 2457-4325 |
| DOI: | 10.22336/rjo.2019.55 |
| Popis: | Objective. This study followed the variability in the foveal avascular zone (FAZ) area measured using optical coherence tomography angiography (OCTA) in patients with type 2 diabetes mellitus and high blood pressure. Material and Methods. This prospective, non-randomized, cohort study evaluated 46 eyes in 26 patients with high blood pressure associated with diabetic non-proliferative retinopathy (mild, medium, and severe forms) and diabetic proliferative retinopathy. Results. Our results showed early macular alterations (microaneurysms, leakage, neovascularizations, intraretinal microvascular abnormalities), a higher class of severity despite a relatively normal clinical aspect and higher values of FAZ associated with neovascularization undetected by SD-OCT (spectral domain-OCT). Conclusion. Measurement of the foveal avascular zone area using OCTA early detects macular alterations that precede classical retinography and SD-OCT determinations. Abbreviations: FAZ = foveal avascular zone; OCTA = optical coherence tomography angiography; IRMA = intraretinal microvascular abnormalities; SD-OCT = spectral domain-optical coherence tomography; OU = both eyes; PD = papillary diameter; ETDRS = early treatment diabetic retinopathy study; BP = blood pressure; OD = right eye. |
| Databáze: | OpenAIRE |
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