Ischaemic burden and changes in absolute myocardial perfusion after chronic total occlusion percutaneous coronary intervention
| Autor: | Henk Everaars, Paul Knaapen, Ronald Boellaard, Roel S. Driessen, Pieter G. Raijmakers, Albert C. van Rossum, Stefan P. Schumacher, Wijnand J. Stuijfzand, Marly Kockx, Alexander Nap, Pepijn A. van Diemen, Maksymilian P. Opolski, Michiel J. Bom |
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| Přispěvatelé: | Cardiology, ACS - Atherosclerosis & ischemic syndromes, Radiology and nuclear medicine, Amsterdam Movement Sciences - Restoration and Development, ACS - Heart failure & arrhythmias, Amsterdam Neuroscience - Brain Imaging, AMS - Tissue Function & Regeneration |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Hyperemia 030204 cardiovascular system & hematology Coronary Angiography 03 medical and health sciences Myocardial perfusion imaging Coronary circulation Percutaneous Coronary Intervention 0302 clinical medicine Coronary Circulation Internal medicine Humans Medicine 030212 general & internal medicine medicine.diagnostic_test business.industry Myocardial Perfusion Imaging Coronary flow reserve Percutaneous coronary intervention Heart Blood flow medicine.anatomical_structure Coronary Occlusion Positron emission tomography Positron-Emission Tomography Conventional PCI Cardiology Cardiology and Cardiovascular Medicine business Perfusion |
| Zdroj: | EuroIntervention, 16(6), E471-E462. EuroPCR Schumacher, S P, Kockx, M, Stuijfzand, W J, Driessen, R S, van Diemen, P A, Bom, M J, Everaars, H, Raijmakers, P G, Boellaard, R, van Rossum, A C, Opolski, M P, Nap, A & Knaapen, P 2021, ' Ischaemic burden and changes in absolute myocardial perfusion after chronic total occlusion percutaneous coronary intervention ', EuroIntervention, vol. 16, no. 6, pp. E471-E462 . https://doi.org/10.4244/EIJ-D-19-00631 |
| ISSN: | 1969-6213 1774-024X |
| DOI: | 10.4244/eij-d-19-00631 |
| Popis: | AIMS: The aim of this study was to explore the relationships between ischaemic burden and changes in absolute myocardial perfusion following chronic coronary total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS AND RESULTS: A total of 193 consecutive patients underwent [15O]H2O positron emission tomography prior to and three months after successful CTO PCI. Change in perfusion defect size, quantitative hyperaemic myocardial blood flow (MBF) and coronary flow reserve (CFR) within the CTO area were compared among patients with limited (0-1 segment, N=15), moderate (2-3 segments, N=61) and large (≥4 segments, N=117) perfusion defects. Median reductions in defect size were 1 [0-1], 2 [1-3], and 4 [2-5] segments in patients with a limited, moderate and large defect (all comparisons p |
| Databáze: | OpenAIRE |
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