Plasma fibronectin concentrations in breast fed and formula fed neonates
Autor: | H E Friss, J Baranowski, L G Rubin, P J Lipsitz, S Carsons |
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Rok vydání: | 1988 |
Předmět: |
Male
medicine.medical_specialty Breast milk Pregnancy Internal medicine medicine Humans Gel electrophoresis Milk Human biology business.industry Colostrum Infant Newborn Bottle Feeding Fibronectins Staining Fibronectin Breast Feeding Endocrinology Pediatrics Perinatology and Child Health Plasma concentration biology.protein Female Infant Food business Breast feeding Formula fed Research Article |
Zdroj: | Archives of Disease in Childhood. 63:528-532 |
ISSN: | 1468-2044 0003-9888 |
DOI: | 10.1136/adc.63.5.528 |
Popis: | Plasma fibronectin concentration was measured in neonates of 2 to 5 days of age. Although breast fed and formula fed infants were similar in demographic characteristics, the mean (SD) plasma concentration of fibronectin in 26 breast fed infants, 237 (117) mg/l, was significantly higher than in 27 formula fed infants (171 (91) mg/l). Fibronectin was detected in five colostrum specimens (mean concentration 13.4 mg/l). Similar bands were detected after gel electrophoresis of purified adult plasma fibronectin and whole plasma from breast fed and formula fed neonates after staining or immunoblotting. Fibronectin isolated from breast milk also appeared similar to purified plasma fibronectin. It is possible, although unlikely, that fibronectin is absorbed intact from ingested colostrum. Alternatively, a factor(s) might be present in colostrum that contributes to the regulation of plasma fibronectin concentration. |
Databáze: | OpenAIRE |
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