| Autor: |
Ryan Chan, Joshua P Hedtke, Michael T Chang, Kristen M Omi, Namrata Kakade, William Y. Luo, Yurianna Hou, Gloria Chin Young, Sunjong Ji, Mai Abdusamad, Amy Ngo, Maggie M Yung, Carissa Chan, Sharon Lee, Mark R Murata, Ashwin Shinde, Jason P Xu, Angelica C Ayala, Emily Jin Kyung Kim, Elitzander Alegria‐Leal, Phuong Vo, Yuan Wan, Vivian K Chen, Raghav Goyal, Anabel Resendiz, Harin B Parikh, Jaime S Tan, Leah C Dorman, Annisa N Soeboer, Seethim Naicker, Pratyush Kandimalla, Petros S Dertsakyan, Faith A Hobby, Beatrice J Sun, Karen Hoi, Megha Pokhriyal, C Kimberly Tsui, Nguyen Khoi Le, Umar Chaudhary, Patrick Chin, Woo Kyeom Kim, Mengshi He, David A Sanville, Utpal Banerjee, Christine Sutanto, Tiffany Luu, Joshua Lin, Tony Yao, Josephine Liu, Janani Muthaiya, Ravinder Kaur, Steven V. Pham, Andrea Vega-Loza, Mia Lim, Nataliya S Balashova, Adam T Quaal, Hnin Hlaing, Patrick A. Truong, Bryan Stender, Harmanjit Bassi, Erwin Feng, Yuxuan Wang, Sarah Salarkia, Rina H Nguyen, Gloria Lam, Garuem Sin, Seong Ah Kim, Sindhuja Godavarthi, Jialing Li, Eileen Hu, Cindy La, Elaine Sang, Jun Ho Chung, Jinhua Shen, Celesti Hao, Josh Mytych, Elliott Wu, Jin Hee Kim, Duy Tran, Neel Chari, Andie O'Laughlin, Christopher J Smith, Mona Abutouk, Chak Lon Kuang, Pei-Hua Tsai, Alisa Sukhina, Li Li, Chongbin He, Daniel Wong, Jahzeel Paguntalan, Emily R Schoen, Edgar Corona, Vivian Yip, Trisha H Patel, Emily Kim, Ira E. Clark, Andrew Char, Guadalupe Ortega Almazan, Asmar Abdul Ghani, Nadiyah Priasti, Duy Q Ngo, Gabrielle Sibal, Sean P Bennion, Stephanie Pang, Vivien W. Ho, Rachel S Distler, Nateli Sama, Josef Madrigal, Maharshi Panchal, Zijie Cai, Ashley C. Hope, Miriam Beyder, Daphne Jin, Steven C Liu, John M. Olson, Janice Ly, Eric Wang, Irene Louie, Wilson Huang, Justin Rafael de la Fuente, Nathan Stutzman, Bilguudei Naranbaatar, Rose Graf, Jonelle Mungcal, Jason Capili, Ziqi Zhou, Kelly M Gu, Julie Ko, Jeffrey A Kho, Amber J Li, Daniel Tran, Cory J. Evans, Jocelyn Woo, Kristen Schnell, Praptee Chowdhury, Chi Ju Lee, Grace J. Lee, Tracy L. Johnson, Nadezhda Riabkova, David Lopatto, Amanda Phan, Mary C Onglatco, Stephanie Huang, Zhiqiao Dong, Sat Kartar Khalsa, Saurin Kadakia, Maique Vo, Jessica Ye, Eric Lin, Darron Miya, Julia A. Ainsworth, Nicholas James, Jonathan Chang, Chloe C Su, Jeffrey Lin, Leslie Jaworski, Jenna Kovsky, Alice Hsu, Michel Chen, Allysen B Ehresman, Ju-Yeon Lee, Talin Golnazarian, Dana Lee, Kai Y Alexander, Jill Zimmerman, Lauren Johnson, Bosco Q Giap, Jamlah Dalie, Jackson K Uriu, Amala John, Osvaldo Acosta, Tebogo Mokwena, Sanan Venkatesh, Brandon L. Tsai, Haris M Akram, Seo-Kyung Oh, Andrea T Fua, Mark A Douglass, Rebecca Yang, Jessica M. Lee, Derek Spitters, Carmen Javier, Alex W Chan, Richard Wong, Ivy H Fu, Connie Y Liu, Parich Tangmatitam, Sena Ji, Claire Park, Arash Ghaffari-Rafi, Vincent T Nguyen, Dorothy Yim, Kush V. Bhatt, Tonatiuh Montoya, Rayna Tian, Vivian Chiu, Malcolm Phung, Victoria Lee, Chinmay Bhoot, Purvi D Patel, Jensen Pak, Puja Yogi, Zhouyang Shen, Nhat-Thi Vo, Bama Charan Mondal, Davis W Popovich, Mane Williams, Oscar M A Del Rio, Alexander J Chassiakos, Ruth Ryu, Zijun Zhao, Renae L Cruz, Yishan Mai, Michael K Wang, Kenneth Chang Chien, Kayla Patel, Jun Wang, Courtney J Cruz, Nicholas J Gills, Alexis Baranoff, Dinali Wijiewarnasurya, Yancey Y Cashell, Iman Hamid, Ashley Hanson, Olivia L Lee, Jasmine Sjarif, Patrick W Chang, Jasmin Johal, Monica Ghaly, Momoko Ishii, Alexandra M Libro, Boyu Cao, Paras Shah, Jennifer Hsueh, Aaron W Bradshaw, Jagteshwar Singh Khatra, Tien M Phan-Everson, Jonathan Lai, David J. Lim, Na Eun Jeon, Caleb Kim, Hyun Wook Kim, Hannah Kim, Sean Full, Tierney G Brannigan, Inho Chang, Suhas P Dasari, Emily R Dennis, Ceejay Lee, Alexander Zai, Christine Zhang, Ayse Elif Kesaf, Ralph Albert, Rebecca M Barber, Shijia W Lu, Austin Ma, Spencer S Hu, Ipsita Dey, Hee Jong Kim, Nancy Ruano, Timothy C Voros, Sarah M. Kamel, Kimberly L Yan, Gah-Eun Jang, Dallas L Mould, Eduardo Hernandez, Sahra M Hosseinian, Iris Chen, Chon Ao, Cindy K Trac, Eric Y Du, Sam Law, Ysrael K Hernandez, Jeffrey S. Zhao, Angad Beniwal, Patricia Yeo, Vina Tran, James R. Lee, Manny Sosa, Zheying Chen, Alec Estrada, Cristian Sosa, Kevin Herrera, Mina Mohammadi, Rina Watanabe, Timothy Chai, Huy Nguyen, Dong Yeon Lee, Vishaal Yepuri, Melanie Huynh, Kyle Marik, Thao T T Nguyen, Xiao X Zhang, Jamie A Ngo, Anh Nguyen, Colton Bracken, Brandon Wei, Brian Aguirre, Sayonika Mohanta, Jeffrey C. Wang, Casey Shapiro, Sonia Gill, Fred Rong, Lauren Petersen, Pingdi Huang, Alexander Grunfeld, Sang Kuk Lee, An N Ha, Kevin Nishida, Shraddha Kumar, Terrence C Lee, Ariano Abbasi, Jenny Summapund, Karl Querubin, Siman Wei, Hanning Xing, Evan Yang, Liset Contreras, Sahar Yaftaly, Matthew Wilson, Ken Siangchin, Brian Kit, Mallory R Neebe, Irvin C Lien, Julia E Petersen, Jonathan Woo, Kaitlyn Honeychurch, Jesse Juarez, Stephen Chang, Raymond Zhou, Cristian Medina, Sean Louise G Laput, Jason T. Lee, Nguon L Tan, Sharon Choi, Natalia C Gutierrez, Zafar S Gill, Kenneth Kim, Jefferson M Dang, Tanveer Salim, Marc Levis-Fitzgerald, Dan Huynh, Joyce Wang, Marsha R Cheng, Lillian Xie, Hannah Markovic, Conny Tran, Mimi Chiang, Vivian Lam, Nick Waite, Ricardo Gray, Jo M Huang |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
G3: Genes|Genomes|Genetics |
| ISSN: |
2160-1836 |
| DOI: |
10.1093/g3journal/jkaa028 |
| Popis: |
Undergraduate students participating in the UCLA Undergraduate Research Consortium for Functional Genomics (URCFG) have conducted a two-phased screen using RNA interference (RNAi) in combination with fluorescent reporter proteins to identify genes important for hematopoiesis in Drosophila. This screen disrupted the function of approximately 3500 genes and identified 137 candidate genes for which loss of function leads to observable changes in the hematopoietic development. Targeting RNAi to maturing, progenitor, and regulatory cell types identified key subsets that either limit or promote blood cell maturation. Bioinformatic analysis reveals gene enrichment in several previously uncharacterized areas, including RNA processing and export and vesicular trafficking. Lastly, the participation of students in this course-based undergraduate research experience (CURE) correlated with increased learning gains across several areas, as well as increased STEM retention, indicating that authentic, student-driven research in the form of a CURE represents an impactful and enriching pedagogical approach. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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