| Autor: |
Elena Medvedeva, Lyudmila Korostovtseva, Mihail Bochkarev, Anastasiya Shumeiko, Aelita Berezina, Maria Simonenko, Yulia Sazonova, Andrey Kozlenok, Yurii Sviryaev |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Clinical Medicine; Volume 11; Issue 13; Pages: 3656 |
| ISSN: |
2077-0383 |
| DOI: |
10.3390/jcm11133656 |
| Popis: |
Background: Sleep-disordered breathing (SDB) is a widespread comorbidity in patients with chronic heart failure (HF) and may have a deleterious effect on the pathogenesis of HF. We aimed to evaluate the prognostic role of polysomnography parameters in HF patients with previous decompensation. Methods: 123 patients were included in the prospective cohort study. In addition to the standard examination, all patients underwent polysomnography (PSG). Results: The Kaplan–Meier analysis showed the incidence of the combined endpoint differs between LVEF categories ≤25.5% vs. >25.5% (χ2 = 9.6, log rank p = 0.002), NTpro-BNP > 680 vs. ≤680 pg/mL (χ2 = 12.7, log rank p = 0.001), VO2peak categories 40 min vs. ≤40 min (χ2 = 9.7, log rank p = 0.03), and sleep stage 2 (S2) 40 min and S2 < 44% were associated with a combined endpoint in patients with previous decompensation of HF. Moreover, higher NT-proBNP and VE/VCO2 slope, lower LVEF, and VO2peak were also independent factors of a poor prognosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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