The Role Of Laboratory Surveillance In Facilitating The Management Of The Coronavirus Disease 2019 (COVID-19) Outbreak In Kelantan
| Autor: | MOHD HATTA Hazlienor, MOHD FUZI Nik Mohd Hafiz, SULAIMAN Suhaiza, MUHAMMAD Abdul Haris, HUSSIN Zaini |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
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| DOI: | 10.5281/zenodo.5457888 |
| Popis: | Background Kelantan had the highest Reproductive (Rt) Value of COVID-19 cases recorded in Malaysia on 22 April 2021, contributing to a quarter of the nation's daily cases. This study aimed to describe the adjustment in testing strategies facilitated by laboratory surveillance in response to the surge of cases. Method All data from the state's COVID-19 registry between January-June 2021 was analyzed for the sampling and testing characteristics including types, frequencies, capacities, positivity rate and laboratory turn-around-time. Descriptive data analysed using SPSS version 25. Results The daily samples received for the diagnostic Nucleic Acid Amplification Test (NAAT) were within capacity throughout Jan-March. In April, the averages test in the second week increased from 1131 tests/day to 1544 tests/day, exceeding the capacity of 1500 tests/day. Afterwards, 16.8% of samples were outsourced, increasing the average testing to 2677 tests/day. However, the average sampling persistently high amounting to 3311/day with positivity rate of 14.2%. Lab turn-around-time exceeded 48 hours; signalling for reactive strategies. Rapid Diagnostic Antigen Testing (Ag-RDT) were then amplified averaging 963/day. In high prevalent localities (>15% positivity rate), cases were confirmed with Ag-RDT without NAAT while negative Ag-RDT among high-risk groups were subjected to NAAT. Conversely, positive Ag-RDT results in low prevalent settings required confirmation by NAAT. On 22 June, NAAT was resumed as the confirmatory test as positivity rate reduced and samples were within the testing capacity. Conclusion Daily laboratory surveillance allowed proactive strategies to be identified in response to different epidemiological conditions, allowing Kelantan to stay within its surge capacity in combatting the COVID-19 pandemic. Disclaimer: Abstract text might vary slightly from what is displayed in the e-poster. This poster was submitted to the 14th National Conference for Clinical Research (NCCR) in August 18-20, 2021. https://nccrconference.com.my/ |
| Databáze: | OpenAIRE |
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