Comparison of Venous Thromboembolism Risks Between COVID-19 Pneumonia and Community-Acquired Pneumonia Patients
| Autor: | Wayne W Zhang, Zhenzhen Liang, Jiawei Fan, Jinhua Yuan, Mingkui Huang, Jianfeng Sun, Fei Mei, Wenfei Guan, Yu Li, Kewei Wang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male China 2019-20 coronavirus outbreak medicine.medical_specialty Adolescent Coronavirus disease 2019 (COVID-19) Pneumonia Viral 030204 cardiovascular system & hematology Betacoronavirus Young Adult 03 medical and health sciences 0302 clinical medicine Community-acquired pneumonia Risk Factors Internal medicine Humans Medicine Hospital Mortality Young adult Child Pandemics Aged Retrospective Studies Aged 80 and over SARS-CoV-2 business.industry Incidence Incidence (epidemiology) Anticoagulants COVID-19 Infant Retrospective cohort study Pneumonia Venous Thromboembolism Middle Aged medicine.disease Community-Acquired Infections Child Preschool 030220 oncology & carcinogenesis Female Coronavirus Infections Cardiology and Cardiovascular Medicine business Venous thromboembolism |
| Zdroj: | Arteriosclerosis, Thrombosis, and Vascular Biology. 40:2332-2337 |
| ISSN: | 1524-4636 1079-5642 |
| DOI: | 10.1161/atvbaha.120.314779 |
| Popis: | Objective: The objectives were to investigate and compare the risks and incidences of venous thromboembolism (VTE) between the 2 groups of patients with coronavirus disease 2019 (COVID-19) pneumonia and community-acquired pneumonia (CAP). Approach and Results: Medical records of 616 pneumonia patients who were admitted to the Yichang Central People’s Hospital in Hubei, China, from January 1 to March 23, 2020, were retrospectively reviewed. The patients with COVID-19 pneumonia were treated in the dedicated COVID-19 units, and the patients with CAP were admitted to regular hospital campus. Risks of VTE were assessed using the Padua prediction score. All the patients received pharmaceutical or mechanical VTE prophylaxis. VTE was diagnosed using Duplex ultrasound or computed tomography pulmonary angiogram. Differences between COVID-19 and CAP groups were compared statistically. All statistical tests were 2 sided, and P P =0.229). In these two groups, 15.6% of the COVID-19 pneumonia patients and 10% of the CAP patients were categorized as high risk for VTE (Padua score, >4), which were significantly different ( P =0.036). In those high-risk patients, the incidence of VTE was 12.5% in COVID-19 pneumonia group and 16.7% in CAP group ( P =0.606). Subgroup analysis of the critically ill patients showed that VTE rate was 6.7% in COVID-19 group versus 13% in CAP group ( P =0.484). In-hospital mortality of COVID-19 and CAP was 6.3% and 3.9%, respectively ( P =0.180). Conclusions: Our study suggested that COVID-19 pneumonia was associated with hypercoagulable state. However, the rate of VTE in COVID-19 pneumonia patients was not significantly higher than that in CAP patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|