Evolution of Bunyaviruses by Genome Reassortment in Dually Infected Mosquitoes ( Aedes triseriatus )
| Autor: | Daniel R. Sundin, Laura J. Chandler, Barry J. Beaty, David H. L. Bishop |
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| Rok vydání: | 1985 |
| Předmět: |
Time Factors
La Crosse virus Genotype Bunyaviridae viruses Reassortment medicine.disease_cause Arbovirus Virus Aedes parasitic diseases medicine Animals Multidisciplinary biology fungi medicine.disease biology.organism_classification Virology Insect Vectors Blood Phenotype Vector (epidemiology) Superinfection Mutation RNA Viral |
| Zdroj: | Science. 230:548-550 |
| ISSN: | 1095-9203 0036-8075 |
| DOI: | 10.1126/science.4048949 |
| Popis: | Aedes triseriatus mosquitoes became dually infected after ingesting two mutants of LaCrosse (LAC) virus simultaneously or after ingesting, by interrupted feeding, the two viruses sequentially within a 2-day period. After 2 weeks of incubation, approximately 25 percent of the vectors contained new virus genotypes as the result of RNA segment reassortment. New viruses were transmitted when the mosquitoes fed on mice. Viruses ingested more than 2 days after the initial infecting virus did not cause superinfection of the mosquito vectors. |
| Databáze: | OpenAIRE |
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