Serological study of vaccinia virus reservoirs in areas with and without official reports of outbreaks in cattle and humans in São Paulo, Brazil
| Autor: | Emerson Legatti, Clóvis R. Fonseca, Acácia Ferreira Vicente, Sabrina de Almeida Moreira, João Marcelo Azevedo de Paula Antunes, Jane Megid, Liria Hiromi Okuda, Thais Silva Bacchiega, José Carlos de Figueiredo Pantoja, Marina Gea Peres, Susan Dora Allendorf, Camila Michele Appolinário, Fernando Ferreira, Edviges Maristela Pituco |
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| Přispěvatelé: | Universidade Estadual Paulista (Unesp), Laboratório de Viroses dos Bovídeos do, Instituto Biológico de São Paulo, Universidade de São Paulo (USP) |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Disease reservoir viruses Rodentia Vaccinia virus Biology Antibodies Viral Virus Disease Outbreaks Serology Young Adult chemistry.chemical_compound Seroepidemiologic Studies Virology Vaccinia medicine Animals Humans Smallpox Seroprevalence GADO Aged Disease Reservoirs virus diseases Outbreak Agriculture General Medicine Middle Aged medicine.disease Vaccination Marsupialia chemistry Animals Domestic Original Article Cattle Brazil |
| Zdroj: | Archives of Virology Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 1432-8798 0304-8608 |
| Popis: | Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:29:40Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:48:33Z : No. of bitstreams: 1 2-s2.0-84878710976.pdf: 279105 bytes, checksum: d4ac8dfda6e7bff4415c43349376a5fc (MD5) Made available in DSpace on 2014-05-27T11:29:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-06-13 Vaccinia virus (VACV), the etiological agent of an exanthematic disease, has been associated with several bovine outbreaks in Brazil since the end of the global vaccination campaign against smallpox. It was previously believed that the vaccine virus used for the WHO global campaign had adapted to an unknown wild reservoir and was sporadically re-emerging in outbreaks in cattle and milkers. At present, it is known that Brazilian VACV is phylogenetically different from the vaccinia virus vaccinal strain, but its origin remains unknown. This study assessed the seroprevalence of orthopoxviruses in domestic and wild animals and farmers from 47 farms in three cities in the southwest region of the state of São Paulo with or without official reports of outbreaks in cattle or humans. Our data indicate a low seroprevalence of antibodies in wild animals and raise interesting questions about the real potential of wild rodents and marsupials as VACV reservoirs, suggesting other routes through which VACV can be spread. © 2013 The Author(s). Faculdade de Medicina Veterinaria e Zootecnia da Universidade Estadual Paulista, Julio de Mesquita F, Botucatu Laboratório de Viroses dos Bovídeos do, Instituto Biológico de São Paulo, São Paulo Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo, São Paulo Faculdade de Medicina Veterinaria e Zootecnia da Universidade Estadual Paulista, Julio de Mesquita F, Botucatu |
| Databáze: | OpenAIRE |
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