Prospect of Stem Cells in Bone Tissue Engineering: A Review
| Autor: | Aswati Subramanian, Hassane Oudadesse, Rosa Akbarzadeh, Conor Flavin, Azizeh-Mitra Yousefi, Paul F. James |
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| Přispěvatelé: | Miami University [Ohio] (MU), Institut des Sciences Chimiques de Rennes (ISCR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ohio Board of Regents, Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
lcsh:Internal medicine Cellular differentiation Mesenchymal stem cell Clinical uses of mesenchymal stem cells Review Article 02 engineering and technology Cell Biology Anatomy Biology 021001 nanoscience & nanotechnology Cell biology 03 medical and health sciences 030104 developmental biology Tissue engineering [CHIM]Chemical Sciences Stem cell 0210 nano-technology Induced pluripotent stem cell Bone regeneration lcsh:RC31-1245 Molecular Biology Stem cell transplantation for articular cartilage repair |
| Zdroj: | Stem Cells International, Vol 2016 (2016) Stem Cells International Stem Cells International, Hindawi Publishing Corporation, 2016, 2016, pp.6180487. ⟨10.1155/2016/6180487⟩ Stem Cells International, 2016, 2016, pp.6180487. ⟨10.1155/2016/6180487⟩ |
| ISSN: | 1687-9678 1687-966X |
| DOI: | 10.1155/2016/6180487⟩ |
| Popis: | International audience; Mesenchymal stem cells (MSCs) have been the subject of many studies in recent years, ranging from basic science that looks into MSCs properties to studies that aim for developing bioengineered tissues and organs. Adult bone marrow-derived mesenchymal stem cells (BM-MSCs) have been the focus of most studies due to the inherent potential of these cells to differentiate into various cell types. Although, the discovery of induced pluripotent stem cells (iPSCs) represents a paradigm shift in our understanding of cellular differentiation. These cells are another attractive stem cell source because of their ability to be reprogramed, allowing the generation of multiple cell types from a single cell. This paper briefly covers various types of stem cell sources that have been used for tissue engineering applications, with a focus on bone regeneration. Then, an overview of some recent studies making use of MSC-seeded 3D scaffold systems for bone tissue engineering has been presented. The emphasis has been placed on the reported scaffold properties that tend to improve MSCs adhesion, proliferation, and osteogenic differentiation outcomes |
| Databáze: | OpenAIRE |
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