Depleted iron stores in voluntary blood donors: A three-center cross-sectional study in Ghana
| Autor: | David Bennin, Patrick Adu, Glory Obadiah Baba, Ama Gyasiwaah Owusu-Poku, Richard Ato Edzie, Toniah Umar Hakeem, Emmanuel Kobina Mesi Edzie |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Cross-sectional study
030204 cardiovascular system & hematology Logistic regression depleted iron stores 03 medical and health sciences 0302 clinical medicine Environmental health Immunology and Allergy Medicine Serum ferritin biology business.industry RED-CELL INDICES lcsh:RC633-647.5 serum ferritin Hematology Venous blood Iron deficiency lcsh:Diseases of the blood and blood-forming organs medicine.disease Ferritin Turnover biology.protein blood donors Original Article calculated red cell indices business 030215 immunology |
| Zdroj: | Asian Journal of Transfusion Science, Vol 14, Iss 2, Pp 149-157 (2020) Asian Journal of Transfusion Science |
| ISSN: | 1998-3565 0973-6247 |
| Popis: | BACKGROUND: Blood donation is frequently associated with iron deficiency. Although iron deficiency is endemic in Ghana, there is a scarcity of data on iron stores in blood donors to inform donor recruitment policy. This study determined the prevalence and factors predictive of depleted iron stores in blood donors. MATERIALS AND METHODS: This cross-sectional study recruited 287 blood donors from three regions in Ghana. Venous blood samples were collected for estimation of C-reactive protein, full blood count, and serum ferritin. Questionnaires were used to capture sociodemographic data. Data were analyzed using SPSS or GraphPad Prism. Multivariate logistic regression and receiver operator characteristics (ROC) analyses were, respectively, used to determine the factors associated with depleted iron stores or sensitivities of calculated red cell indices in predicting depleted iron stores in the participants. RESULTS: Whereas 27.4% of the blood donors had depleted iron stores (ferritin |
| Databáze: | OpenAIRE |
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