Dinuclear Ruthenium(II) Triple-Stranded Helicates: Luminescent Supramolecular Cylinders That Bind and Coil DNA and Exhibit Activity against Cancer Cell Lines
| Autor: | Anna C. G. Hotze, Carlos Sanchez-Cano, Benson M. Kariuki, Michael J. Hannon, Gabriel I. Pascu |
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| Rok vydání: | 2007 |
| Předmět: |
Models
Molecular Luminescence Stereochemistry Macromolecular Substances Supramolecular chemistry chemistry.chemical_element Antineoplastic Agents Crystallography X-Ray Ligands Catalysis Ruthenium chemistry.chemical_compound Structure-Activity Relationship Cell Line Tumor Organometallic Compounds Molecule Structure–activity relationship Humans Binding site Group 2 organometallic chemistry Binding Sites Molecular Structure fungi General Chemistry DNA General Medicine Fluorescence chemistry Drug Screening Assays Antitumor |
| Zdroj: | Angewandte Chemie. 119:4452-4456 |
| ISSN: | 1521-3757 0044-8249 |
| DOI: | 10.1002/ange.200700656 |
| Popis: | (Figure presented) A fluorescent supramolecular cylinder binds noncovalently to DNA and shows anticancer activity in cell lines. © 2007 Wiley-VCH Verlag GmbH and Co. KGaA. |
| Databáze: | OpenAIRE |
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