CD86 occupancy in belatacept-treated kidney transplant patients is not associated with clinical and infectious outcomes

Autor:	Tristan de Nattes, Ludivine Lebourg, Isabelle Etienne, Charlotte Laurent, Mathilde Lemoine, Audrey Dumont, Dominique Guerrot, Serge Jacquot, Sophie Candon, Dominique Bertrand
Rok vydání:	2022
Předmět:	Abatacept Graft Rejection Transplantation Humans Immunology and Allergy Pharmacology (medical) Kidney Transplantation Antibodies Immunosuppressive Agents
Zdroj:	American Journal of Transplantation. 22:1691-1698
ISSN:	1600-6135
DOI:	10.1111/ajt.17005
Popis:	The CD86 occupancy assay has been developed to measure the number of CD86 molecules unbound to belatacept, but its association with clinical outcomes has not been assessed yet. All kidney transplant patients switched to belatacept in our center between 2016 and 2018 were included. Blood samples were collected before each infusion for 1 year to assess CD86 occupancy by CD86 antibody cytometry staining on the surface of CD14
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e31940def279c9ff7c7db6e70e7c7f https://doi.org/10.1111/ajt.17005 Zobrazit plný text záznamu Plný text