Autosomal Dominant Polycystic Kidney Disease
| Autor: | Darin P. Trelka, Parvathi Perumareddi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Autosomal dominant polycystic kidney disease Secondary hypertension Renal function Gastroenterology End stage renal disease Sex Factors Risk Factors Internal medicine medicine Polycystic kidney disease Humans Pharmacology (medical) Referral and Consultation Dialysis Kidney Primary Health Care business.industry Age Factors medicine.disease Polycystic Kidney Autosomal Dominant medicine.anatomical_structure Disease Progression Kidney Failure Chronic Kidney stones business Antidiuretic Hormone Receptor Antagonists |
| Zdroj: | Primary care. 47(4) |
| ISSN: | 1558-299X |
| Popis: | Autosomal Dominant Polycystic Kidney Disease is an inherited multisystemic disorder of the renal tubules with subsequent formation of multiple cysts and enlargement of the kidney, affecting various organs. Diagnosis is initially suspected in those with family history and/or individuals who develop hypertension early on (secondary hypertension) or certain symptoms. Renal function is initially preserved for years secondary to compensatory mechanisms. Associated conditions include: liver cysts, berry aneurysms, kidney stones, etc. The disease course is variable, but patients often progress to end-stage renal failure by age 60. There is no known cure, however, risk factor modification at early stages is critical. Renal transplant is the optimal treatment in ESRD. |
| Databáze: | OpenAIRE |
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