A new alkaloid from Thespesia populnea endophytic fungus Penicillium sp. TM-Y1-1

Autor:	Tang, Jing, Wu, Li, Tang, Xin-Fan, Liu, Wen-Bin, Chen, Chen, Li, Jia-Lin, Long, Yu-Hua
Rok vydání:	2022
Předmět:	Pharmacology Complementary and alternative medicine Organic Chemistry Drug Discovery Pharmaceutical Science Molecular Medicine General Medicine Analytical Chemistry
Zdroj:	Journal of Asian Natural Products Research. :1-7
ISSN:	1477-2213 1028-6020
DOI:	10.1080/10286020.2022.2162887
Popis:	A new alkaloid (3), together with three known compounds, were isolated from the Thespesia populnea endophytic fungus TM-Y1-1. Their structures were elucidated by extensive spectroscopic methods. The absolute configuration of compound 3 was determined for the first time by ECD calculation and DP4+ analysis. All compounds were evaluated for antimicrobial activity. The results showed that compounds 1 and 2 both exhibited moderate inhibitory activity against banana Colletotrichum gloeosporioides with MIC value of 31.25 μg/ml.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e2308ff55537889abfcc1ecbc93d15 https://doi.org/10.1080/10286020.2022.2162887 Zobrazit plný text záznamu