A metabolite fingerprinting for the characterization of commercial botanical dietary supplements
Autor: | Lisa Bellotto, Caterina Ghiara, Anna Maidecchi, Luisa Mattoli, Roberta Seraglia, Michela Burico, Erika Bianchi, Eugenio Ragazzi, Pietro Traldi, Francesca Cangi |
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Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: |
Chromatography
High interest Electrospray mass spectrometry Endocrinology Diabetes and Metabolism Electrospray ionization Metabolite Clinical Biochemistry Biochemistry chemistry.chemical_compound chemistry Metabolic fingerprinting Botanical dietary supplements Direct infusion Spectral data Metabolic profile |
Zdroj: | Metabolomics (Dordrecht. Print) 7 (2011): 437–445. doi:10.1007/s11306-010-0268-x info:cnr-pdr/source/autori:Mattoli L.; Cangi F.; Ghiara C.; Burico M.; Maidecchi A.; Bianchi E.; Ragazzi E.; Bellotto L.; Seraglia R.; Traldi P./titolo:A metabolite fingerprinting for the characterization of commercial botanical dietary supplements/doi:10.1007%2Fs11306-010-0268-x/rivista:Metabolomics (Dordrecht. Print)/anno:2011/pagina_da:437/pagina_a:445/intervallo_pagine:437–445/volume:7 |
Popis: | Phytopharmaceuticals, phytomedicines and botanical dietary supplements are products of wide interest considering the increase of their use. The development of fast and effective analytical methods able to give a fingerprinting of the product, on the basis of the plant extracts declared to be contained in it, is surely of high interest. In a previous investigation electrospray mass spectrometry was proved to be effective for the characterization of plant extracts. The direct infusion of the samples and the analyses in both positive and negative ion mode lead to a clear differentiation of the different samples. To verify if the same approach can be effective also for mixtures of plant extracts, five different commercial dietary supplements [Sedivitax gocce (1), Finocarbo Plus opercoli (2), Sollievo Bio tavolette (3), MiniMas opercoli (4) and Ruscoven gocce (5), all products from Aboca S. p. A., Sansepolcro, Italy] were analyzed by ESI. In order to evaluate possible changes in the metabolic profile with respect to different years of production, ten different batches of the commercial dietary supplements were considered. The mass spectral data were evaluated by multivariate analysis and the obtained results suggest that the method allows a satisfactory and rapid characterization of complex mixtures of commercial dietary supplements. © 2010 Springer Science+Business Media, LLC. |
Databáze: | OpenAIRE |
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