A Randomized, Crossover Study of the Acute Cognitive and Cerebral Blood Flow Effects of Phenolic, Nitrate and Botanical Beverages in Young, Healthy Humans
| Autor: | Rachel C. Veasey, Caroline Saunders, Emma L. Wightman, David O. Kennedy, Siobhan Mitchell, Julie Khan, Philippa A. Jackson, Joanne Forster, Crystal F. Haskell-Ramsay |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Flavonols near-infrared spectroscopy Blueberry Plants Phytochemicals cerebral blood flow Berry B400 Coffee Anthocyanins Ginseng chemistry.chemical_compound Cognition 0302 clinical medicine Food science Cross-Over Studies Nutrition and Dietetics food and beverages Middle Aged Healthy Volunteers Cerebral blood flow Cerebrovascular Circulation Malus Female Beta vulgaris Chlorogenic Acid lcsh:Nutrition. Foods and food supply Adult Adolescent lcsh:TX341-641 Biology Article Beverages Young Adult 03 medical and health sciences Double-Blind Method Chlorogenic acid Humans Energetic arousal polyphenols Nitrates 030109 nutrition & dietetics Plant Extracts SAGE Crossover study C800 Affect chemistry Polyphenol 030217 neurology & neurosurgery dietary nitrate Food Science |
| Zdroj: | Nutrients Volume 12 Issue 8 Nutrients, Vol 12, Iss 2254, p 2254 (2020) |
| ISSN: | 2072-6643 |
| Popis: | Background: In whole foods, polyphenols exist alongside a wide array of other potentially bioactive phytochemicals. Yet, investigations of the effects of combinations of polyphenols with other phytochemicals are limited. Objective: The current study investigated the effects of combining extracts of beetroot, ginseng and sage with phenolic-rich apple, blueberry and coffee berry extracts. Design: This randomized, double-blind, placebo-controlled crossover design investigated three active beverages in 32 healthy adults aged 18&ndash 49 years. Each investigational beverage comprised extracts of beetroot, ginseng and sage. Each also contained a phenolic-rich extract derived from apple (containing 234 mg flavanols), blueberry (300 mg anthocyanins) or coffee berry (440 mg chlorogenic acid). Cognition, mood and CBF parameters were assessed at baseline and then again at 60, 180 and 360 min post-drink. Results: Robust effects on mood and CBF were seen for the apple and coffee berry beverages, with increased subjective energetic arousal and hemodynamic responses being observed. Fewer effects were seen with the blueberry extract beverage. Conclusions: Either the combination of beetroot, ginseng and sage was enhanced by the synergistic addition of the apple and coffee berry extract (and to a lesser extent the blueberry extract) or the former two phenolic-rich extracts were capable of evincing the robust mood and CBF effects alone. |
| Databáze: | OpenAIRE |
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