Heart rate recovery in asthmastic children and adolescents after clinical field test
Autor: | Dirceu Solé, Simone Dal Corso, Karina Silva Nascimento, Mariana Mazzuca Reimberg, Raphael Mendes Ritti-Dias, Gustavo F. Wandalsen, Fernanda de Cordoba Lanza, Bruno A. Soares, Fabiana Silvia Anjos, Élida Pereira Silva |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Adolescent Population 030204 cardiovascular system & hematology law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Shapiro–Wilk test Heart Rate law Modified shuttle test Forced Expiratory Volume Statistical significance Internal medicine Heart rate medicine Humans Child education Asthma lcsh:RC705-779 education.field_of_study Exercise Tolerance business.industry lcsh:Diseases of the respiratory system medicine.disease Clinical trial Heart rate recovery 030228 respiratory system Spirometry Exercise Test Mann–Whitney U test Female business human activities Brazil Research Article |
Zdroj: | BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-6 (2021) BMC Pulmonary Medicine |
ISSN: | 1471-2466 |
Popis: | Background Inflammation caused by chronic lung disease in childhood may lead to delayed heart rate recovery (HRR) however, there is lack of evidence on HRR in this population. The aim was to assess HRR after functional capacity testing in asthmatic children and adolescents and to compare with severity and disease control. Method This was a study secondary to a randomized control trial. The modified shuttle test (MST) was performed to assess functional capacity and HRR. This is an externally cadenced test in which the distance walked is the outcome. HRR was assessed after MST and was defined as HR at exercise peak minus HR in the second minute after the end of exercise. Asthma control was assessed by the Asthma Control Test (ACT). Data normality was tested by Shapiro Wilk and the comparison between groups was made by Student’s t test or Mann Whitney test for numerical variables, and by Chi-square test for categorical variables. Statistical significance was considered when p Results The sample included 77 patients diagnosed with asthma (asthma group - AG) who were regularly treated for asthma. Control group (CG) consisted of 44 volunteers considered healthy, matched in age and gender to AG. The median age of CG was 12 (10–14) years and in AG 11 (9–13 years) being classified as mild to moderate asthmatic, and 57% of the sample had controlled asthma by ACT. Distance walked in the CG was 952 ± 286 m and AG 799 ± 313 m, p = 0.001. HRR was more efficient in CG (79 ± 15 bpm) compared to AG (69 ± 12 bpm), p = 0.001. The mild (69 ± 12 beats) and severe (72 ± 15 beats) AG presented worse HRR compared to control group (79 ± 15 bpm), p Conclusions Asthmatic children and adolescents have delayed HRR after modified Shuttle test compared to their peers, suggesting that asthma leads to autonomic nervous system imbalance. Trial registration: Registered in Clinical Trials under number NCT02383069 and approved by the Universidade Nove de Julho - UNINOVE Research Ethics Committee, protocol number 738192/2014. |
Databáze: | OpenAIRE |
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