The conception of the ABCD study: From substance use to a broad NIH collaboration
| Autor: | William T. Riley, Antonio Noronha, Gayathri J. Dowling, Diana W. Bianchi, Joshua A. Gordon, Walter J. Koroshetz, Glen D. Morgan, Eliseo J. Pérez-Stable, Kevin P. Conway, Susan R.B. Weiss, Robert T. Croyle, John A. Matochik, Katia D. Howlett, Kenneth R. Warren, George F. Koob, Michele Bloch, Catherine Y. Spong, Eric M. Wargo, Margaret M. Murray, Bethany Griffin Deeds, Nora D. Volkow, Steven Grant |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Value (ethics) Longitudinal study medicine.medical_specialty Adolescent Substance-Related Disorders Cognitive Neuroscience Brain Structure and Function Neuroimaging Article Developmental psychology 03 medical and health sciences 0302 clinical medicine Cognition medicine Cognitive development Humans Longitudinal Studies Public health lcsh:QP351-495 Brain Adolescent Development Mental illness medicine.disease Mental health United States 030104 developmental biology lcsh:Neurophysiology and neuropsychology National Institutes of Health (U.S.) Informatics Female Psychology 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Developmental Cognitive Neuroscience, Vol 32, Iss, Pp 4-7 (2018) |
| ISSN: | 1878-9293 |
| Popis: | Adolescence is a time of dramatic changes in brain structure and function, and the adolescent brain is highly susceptible to being altered by experiences like substance use. However, there is much we have yet to learn about how these experiences influence brain development, how they promote or interfere with later health outcomes, or even what healthy brain development looks like. A large longitudinal study beginning in early adolescence could help us understand the normal variability in adolescent brain and cognitive development and tease apart the many factors that influence it. Recent advances in neuroimaging, informatics, and genetics technologies have made it feasible to conduct a study of sufficient size and scope to answer many outstanding questions. At the same time, several Institutes across the NIH recognized the value of collaborating in such a project because of its ability to address the role of biological, environmental, and behavioral factors like gender, pubertal hormones, sports participation, and social/economic disparities on brain development as well as their association with the emergence and progression of substance use and mental illness including suicide risk. Thus, the Adolescent Brain Cognitive Development study was created to answer the most pressing public health questions of our day. Keywords: Adolescent, Brain development, Neuroimaging, Longitudinal, Substance use, Mental health |
| Databáze: | OpenAIRE |
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