Mobilization of the gentamicin resistance gene in Enterococcus faecalis
| Autor: | Barbara E. Murray, S. L. Hodel-Christian |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Transposable element
animal structures HindIII Enterococcus faecalis Microbiology HaeIII Restriction fragment Plasmid medicine Pharmacology (medical) Pharmacology biology fungi Aminoglycoside Drug Resistance Microbial biochemical phenomena metabolism and nutrition biology.organism_classification Molecular biology body regions Infectious Diseases Genes Bacterial DNA Transposable Elements biology.protein Gentamicin Gentamicins DNA Probes Polymorphism Restriction Fragment Length Research Article Plasmids medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 34:1278-1280 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.34.6.1278 |
| Popis: | Enterococcus faecalis plasmid pBEM10 (a conjugative plasmid encoding beta-lactamase production and gentamicin resistance [Gmr]) was made transfer deficient by using Tn917. Relocation of the Gmr determinant into two sites on pCF10 was observed. Restriction analysis revealed insertion of a common 2.5-kilobase-pair HindIII and a 3.9-kilobase-pair HaeIII fragment encoding Gmr, suggesting that this determinant resides on a transposon similar to Tn4001. |
| Databáze: | OpenAIRE |
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