Kikuchi-Fujimoto Disease: A Case Report and Literature Review
| Autor: | Albert Lim, Wolfgang Issing, Vikrant Veer |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pathology
medicine.medical_specialty education.field_of_study medicine.diagnostic_test business.industry Population Case Report Physical examination General Medicine lcsh:Otorhinolaryngology Malignancy medicine.disease lcsh:RF1-547 Lymphoma Etiology Medicine Lymph medicine.symptom business education Odynophagia Histiocyte |
| Zdroj: | Case Reports in Otolaryngology, Vol 2012 (2012) Case Reports in Otolaryngology |
| ISSN: | 2090-6773 2090-6765 |
| DOI: | 10.1155/2012/497604 |
| Popis: | Case. 38-year-old lady was referred to the ENT clinic with history of right-sided facial pain, otalgia, and odynophagia. Clinical examination revealed enlarged right-sided lymph nodes in the neck. Further radiological scans showed a mass near the carotid and enlarged level V lymph nodes. Lymphoma was initially suspected. Fine-needle aspiration and excision biopsy were undertaken. Histological analysis later suggested Kikuchi-Fujimoto disease, also known as histiocytic necrotising lymphadenitis.Literature Review. Kikuchi-Fujimoto disease (KFD) was described in 1972 as lymphadenitis with focal proliferation of reticular cells accompanied by numerous histiocytes and extensive nuclear debris. KFD, frequently found in East Asian countries, is rare in the UK. No definite aetiology of KFD is known despite autoimmune and infection factors being suggested. The diagnostic hallmark is histological findings from lymph nodes. Malignancy should be excluded. This condition is mainly self-limiting; hence, management is limited to supportive care. Steroid therapy could be used in severe cases. KFD is relatively unknown in the UK and this case report aims to highlight its occurrence in our population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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