Comparing intraoperative parathyroid identification based on surgeon experience versus near infrared autofluorescence detection - A surgeon-blinded multi-centric study
| Autor: | Naira Baregamian, Fei Ye, Lawrence A. Shirley, Anita Mahadevan-Jansen, Rebecca Irlmeier, Emmanuel A. Mannoh, Carmen C. Solorzano, Paul G. Gauger, Tyler Metcalf, Alexa Magner, John E. Phay, Jon A. Nelson, Giju Thomas, Samuel E. Long, Rekha Gautam |
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| Rok vydání: | 2020 |
| Předmět: |
Parathyroidectomy
Adult Male medicine.medical_specialty medicine.medical_treatment 030230 surgery Article Parathyroid Glands 03 medical and health sciences Intraoperative Period Young Adult 0302 clinical medicine medicine Endocrine system Humans Aged Aged 80 and over Spectroscopy Near-Infrared business.industry Optical Imaging Thyroidectomy General Medicine Gold standard (test) Middle Aged Autofluorescence surgical procedures operative medicine.anatomical_structure 030220 oncology & carcinogenesis Surgery Parathyroid gland Female Radiology Clinical Competence business |
| Zdroj: | Am J Surg |
| ISSN: | 1879-1883 |
| Popis: | BACKGROUND: Near infrared autofluorescence (NIRAF) detection has previously demonstrated significant potential for real-time parathyroid gland identification. However, the performance of a NIRAF detection device - PTeye® - remains to be evaluated relative to a surgeon’s own ability to identify parathyroid glands. METHODS: Patients eligible for thyroidectomy and/or parathyroidectomy were enrolled under 6 endocrine surgeons at 3 high-volume institutions. Participating surgeons were categorized based on years of experience. All surgeons were blinded to output of PTeye® when identifying tissues. The surgeon’s performance for parathyroid discrimination was then compared with PTeye®. Histology served as gold standard for excised specimens, while expert surgeon’s opinion was used to validate in-situ tissues. RESULTS: PTeye® achieved 92.7% accuracy across 167 patients recruited. Junior surgeons (10 years of experience). CONCLUSIONS: NIRAF detection with PTeye® can be a valuable intraoperative adjunct technology to aid in parathyroid identification for surgeons. |
| Databáze: | OpenAIRE |
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