Supplementary Materials and Methods, Figures 1 - 14, Table 1 from Molecular Biomarkers of Residual Disease after Surgical Debulking of High-Grade Serous Ovarian Cancer

Autor: Anil K. Sood, Keith A. Baggerly, Wei Hu, Cristina Ivan, Bulent Ozpolat, Gabriel Lopez-Berestein, Rajesha Rupaimoole, Sherry Y. Wu, Heather J. Dalton, Jamie Guenthoer, Robert L. Coleman, Erin K. Crane, Alpa M. Nick, Anna K. Unruh, Shelley M. Herbrich, Kshipra Gharpure, Susan L. Tucker
Rok vydání: 2023
Popis: PDF file - 2766KB, Supplementary methods and reports describing all data analyses. Supplementary Table 1. Probesets (N=47) and associated genes (N=38) having consistent differences in expression between residual disease (RD) and No-RD patients in the TCGA and Tothill data sets at a 10 percent false discovery rate in each data set. Figure 1. Bivariate plot of two-sample RD-No RD t-values for TCGA and Tothill. The vast majority of the probesets selected show higher expression in RD cases. Lumican (LUM) is the strongest overall. Figure 2. Zoom on the upper quadrant of the bivariate plot of two-sample RD-No RD t-values for TCGA and Tothill, to show the names more clearly. Figure 3. Heatmap of the TCGA Samples using just the 8 probesets passing the 5 percent FDR filter for both TCGA and Tothill. Figure 4. Heatmap of the Tothill Samples using just the 8 probesets passing the 5 percent FDR filter for both TCGA and Tothill. Figure 5. Heatmap of the TCGA Samples using the 47 probesets passing the 10 percent FDR filter for both TCGA and Tothill. Figure 6. Heatmap of the Tothill Samples using the 47 probesets passing the 10 percent FDR filter for both TCGA and Tothill. Figure 7. Correlations in the TCGA data between the 47 probesets selected by 10 percent FDR cutoffs. Figure 8. Correlations in the Tothill data between the 47 probesets selected by 10 percent FDR cutoffs. Figure 9. Dot and density plots for lumican (LUM) in TCGA and Tothill. Figure 10. Dot and density plots for decorin (DCN) in TCGA and Tothill. Figure 11. Dot and density plots for GADD45B in TCGA and Tothill. Figure 12. Dot and density plots for FABP4 in TCGA and Tothill. Figure 13. Dot and density plots for ADH1B in TCGA and Tothill. Figure 14. Dot and density plots for ADIPOQ in TCGA and Tothill.
Databáze: OpenAIRE