Nucleoside Analogues Achieve High Concentrations in Seminal Plasma: Relationship between Drug Concentration and Virus Burden
| Autor: | Arlene S. Pereira, Richard R Tidwell, Joseph J. Eron, Luigi Troiani, John A. Dunn, Susan A. Fiscus, Myron S. Cohen, James Edwin Hall, Angela D. M. Kashuba |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Sexual transmission Anti-HIV Agents HIV Infections Semen Virus Andrology Zidovudine medicine Humans Immunology and Allergy biology RNA Lamivudine Middle Aged Viral Load biology.organism_classification Virology Infectious Diseases Lentivirus HIV-1 RNA Viral Drug Therapy Combination Viral load medicine.drug |
| Zdroj: | The Journal of Infectious Diseases. 180:2039-2043 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1086/315149 |
| Popis: | Human immunodeficiency virus (HIV) can be transmitted in semen from a man to his sexual partners. Antiretroviral drugs are likely to affect the amount of HIV-1 in semen and perhaps transmission of the virus. The concentrations of zidovudine, lamivudine, and HIV-1 RNA in blood and seminal plasma were measured in 9 HIV-positive men over |
| Databáze: | OpenAIRE |
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