A Comparison of Multiple Urine Markers for Interstitial Cystitis
| Autor: | Marcia A. Wheeler, Susan Keay, Deborah R. Erickson, Lawrence M. Demers, Sharon X. Xie, Robert E. Hurst, Veer P. Bhavanandan, Leslie Kushner |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
biology business.industry Urology medicine.medical_treatment Methylhistamine Interstitial cystitis Interleukin Urine medicine.disease Insulin-like growth factor chemistry.chemical_compound Endocrinology chemistry Epidermal growth factor Internal medicine biology.protein Medicine business Interleukin 6 Cyclic guanosine monophosphate |
| Zdroj: | Journal of Urology. 167:2461-2469 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(05)65005-7 |
| Popis: | Purpose: We measured several urine markers in 24-hour specimens from patients with interstitial cystitis and healthy controls. For each marker we determined whether the urine level was significantly different in interstitial cystitis and control cases, and whether the marker level correlated with the symptom score.Materials and Methods: Study participants included 36 female patients with interstitial cystitis and 36 age matched female volunteers. Multiple urine aliquots were obtained to measure the various markers.Results: Certain markers were significantly increased in interstitial cystitis, including anti-proliferative factor, epidermal growth factor, insulin-like growth factor (IGF) binding protein-3 and interleukin (IL)-6. Markers significantly decreased in interstitial cystitis were heparin-binding epidermal growth factor-like growth factor, cyclic guanosine monophosphate and methylhistamine. Other markers were not significantly different in the interstitial cystitis and control groups, including tot... |
| Databáze: | OpenAIRE |
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