Chemical composition, phytochemical constituents, antioxidant and anti-inflammatory activities of Urtica urens L. leaves
| Autor: | Tarek Rebai, Sana Bardaa, Zouheir Sahnoun, Massara Mzid, Sameh Ben Khedir |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Male Antioxidant Physiology medicine.drug_class medicine.medical_treatment Phytochemicals Anti-Inflammatory Agents medicine.disease_cause Carrageenan Anti-inflammatory Antioxidants 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Physiology (medical) Malondialdehyde medicine Animals Edema Urticaceae Chemical composition biology Traditional medicine Chemistry Plant Extracts General Medicine biology.organism_classification Rats Plant Leaves Oxidative Stress 030104 developmental biology Phytochemical Urtica urens 030220 oncology & carcinogenesis Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization Oxidative stress Chromatography Liquid Phytotherapy |
| Zdroj: | Archives of physiology and biochemistry. 123(2) |
| ISSN: | 1744-4160 |
| Popis: | The aim of this study was to investigate the chemical composition and antioxidant properties of Urtica urens L.(Uu) as well as its anti-inflammatory effect on carrageenan (CARR)-induced paw oedema in rats.The leaves were extracted using ethanol (EtOH) and water. The extracts were analysed for proximate composition and antioxidant activity using standard chemical analysis methods.The proximate analysis showed that Uu leaves contained appreciable percentages of dry mass, ashes, carbohydrates, proteins, lipids, sugars, anthocyanin, carotenoid and fibre. Results showed that EtOH extract contained the highest amount of total phenolics, flavonoids, tannins, ortho-diphenols and flavonols. It decreased the paw oedema after CARR administration, and ameliorated the activities of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), and the malondialdehyde (MDA).Uu displayed a high potential as a natural source of minerals, phytochemicals and antioxidant properties. EtOH extract exhibited a significant inhibition against CARR-induced inflammation. |
| Databáze: | OpenAIRE |
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