Sensory endings in skin grafts and scars after extensive burns
| Autor: | Maurizio Stella, Maurizio Calcagni, Giancarlo Panzica, G. Cellino, Guglielmo Ramieri, S. Teich-Alasia |
|---|---|
| Přispěvatelé: | University of Zurich, Stella, M |
| Rok vydání: | 1994 |
| Předmět: |
Pathology
medicine.medical_specialty Sensory Receptor Cells Scars 610 Medicine & health Sensory system Critical Care and Intensive Care Medicine Cicatrix Injury Severity Score Dermis medicine Humans 10266 Clinic for Reconstructive Surgery Skin Analysis of Variance integumentary system business.industry Skin Transplantation General Medicine Anatomy Immunohistochemistry 2746 Surgery medicine.anatomical_structure Dermal papillae Emergency Medicine Surgery Epidermis medicine.symptom Burns 2711 Emergency Medicine 2706 Critical Care and Intensive Care Medicine business Free nerve ending Reinnervation |
| Zdroj: | Burns. 20:491-495 |
| ISSN: | 0305-4179 |
| DOI: | 10.1016/0305-4179(94)90003-5 |
| Popis: | Fifteen patients who underwent a split thickness skin graft operation for full thickness burns and six patients with postburn scars were biopsied after a standard aesthesiological examination completed with Weber and Dellon tests. A semiquantitative evaluation was performed on immunohistochemically stained sections to determine the presence or absence of PGP 9.5 immunoreactive intraepithelial fibres, complex sensory receptors, nerve fibres in the dermal papillae, vessel-innervating fibres, gland-innervating fibres, and nerve trunks in the deep dermis. The reinnervation pattern was similar in grafts and scars. With regard to sensory receptors, free nerve endings and Merkel-neurite complexes were observed. Statistical analysis suggested a significant correlation between sensibility and the amount of regenerated nerve structures (particularly in the epidermis and dermal papillae). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|