Effects of Apigenin on the Expression of LOX‐1, Bcl‐2, and Bax in Hyperlipidemia Rats

Autor:	Li Na Wang, Yan-Hong Xiao, Qian Xu, Yan-Chao Li, Chao Du
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty Gene Expression Blood lipids Hyperlipidemias Bioengineering Biochemistry Rats Sprague-Dawley chemistry.chemical_compound Internal medicine Gene expression Hyperlipidemia medicine Animals Apigenin Molecular Biology Normal control Aorta Triglycerides bcl-2-Associated X Protein Lipoprotein cholesterol Triglyceride General Chemistry General Medicine Scavenger Receptors Class E medicine.disease Rats Disease Models Animal Cholesterol Endocrinology Proto-Oncogene Proteins c-bcl-2 chemistry Molecular mechanism Molecular Medicine lipids (amino acids peptides and proteins)
Zdroj:	Chemistry & Biodiversity. 18
ISSN:	1612-1880 1612-1872
Popis:	We aimed to investigate the impact of apigenin on LOX-1, Bcl-2, and Bax expression in hyperlipidemia rats and explore the possible molecular pathological mechanism of apigenin in improving hyperlipidemia and preventing atherosclerosis. In hyperlipidemia models, the levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-c) and the LOX-1 protein expression were apparently increased (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4797b527f17489b98caf8becbdb53273 https://doi.org/10.1002/cbdv.202100049 Zobrazit plný text záznamu Plný text