Pathophysiology and Treatment of Pruritus in Elderly
| Autor: | Ji Young Um, Hye One Kim, Bo Young Chung, Jin Cheol Kim, Chun Wook Park, Seok Young Kang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Review elderly Catalysis senile pruritus lcsh:Chemistry Inorganic Chemistry 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine neurotransmission pathophysiology of itch medicine Elderly people Humans 030212 general & internal medicine itch Physical and Theoretical Chemistry skin and connective tissue diseases lcsh:QH301-705.5 Molecular Biology pruritogen Spectroscopy Aged integumentary system business.industry Psychogenic pruritus Pruritus Organic Chemistry Disease Management treatment of itch General Medicine medicine.disease Dermatology Pathophysiology Computer Science Applications body regions Multiple factors lcsh:Biology (General) lcsh:QD1-999 ion channel Quality of Life business Chronic pruritus Senile pruritus |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 22, Iss 174, p 174 (2021) |
| ISSN: | 1422-0067 |
| Popis: | Pruritus is a relatively common symptom that anyone can experience at any point in their life and is more common in the elderly. Pruritus in elderly can be defined as chronic pruritus in a person over 65 years old. The pathophysiology of pruritus in elderly is still unclear, and the quality of life is reduced. Generally, itch can be clinically classified into six types: Itch caused by systemic diseases, itch caused by skin diseases, neuropathic pruritus, psychogenic pruritus, pruritus with multiple factors, and from unknown causes. Senile pruritus can be defined as a chronic pruritus of unknown origin in elderly people. Various neuronal mediators, signaling mechanisms at neuronal terminals, central and peripheral neurotransmission pathways, and neuronal sensitizations are included in the processes causing itch. A variety of therapies are used and several novel drugs are being developed to relieve itch, including systemic and topical treatments. |
| Databáze: | OpenAIRE |
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