Induction of spermiation in common carp after enhanced intestinal uptake of sGnRH-A and Pimozide
| Autor: | T. Mikolajczyk, P. Epler, Ivo Roelants, Bernard Breton, J. Chyb, Frans Ollevier |
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| Přispěvatelé: | Station commune de Recherches en Ichtyophysiologie, Biodiversité et Environnement (SCRIBE), Institut National de la Recherche Agronomique (INRA) |
| Rok vydání: | 2000 |
| Předmět: |
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences
Milt endocrine system medicine.medical_specialty CARPE COMMUNE CYPRINIDAE CYPRINUS CARPIO Aquatic Science Biology Intestinal absorption 03 medical and health sciences Common carp Pimozide Oral administration Internal medicine medicine Carp ComputingMilieux_MISCELLANEOUS Ecology Evolution Behavior and Systematics 030304 developmental biology 0303 health sciences 04 agricultural and veterinary sciences biology.organism_classification Gonadotropin secretion Endocrinology Drug delivery 040102 fisheries 0401 agriculture forestry and fisheries medicine.drug |
| Zdroj: | Journal of Fish Biology Journal of Fish Biology, Wiley, 2000, 56, pp.1398-1407 |
| ISSN: | 1095-8649 0022-1112 |
| DOI: | 10.1111/j.1095-8649.2000.tb02152.x |
| Popis: | The inherent ability of the carp Cyprinus carpio gut to absorb intact salmon gonadotropin hormone-releasing hormone analogue (sGnRH-a)+Pimozide (Pim), without loss of their bioactivity is very limited. Artificial intestinal absorption enhancement boosted sGnRH-a and Pim induced GtH II release and milt production significantly. The intraperitoneal route of administration was more effective than the oral one. A potential application of the oral route for peptidergic drug delivery and the possibility of developing a dietary delivery system is discussed. |
| Databáze: | OpenAIRE |
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