Temporary impairment of reproduction in freshwater teleost exposed to nonylphenol
| Autor: | Guido Bortoluzzi, Ike Olivotto, Oliana Carnevali, Alberta Maria Polzonetti-Magni, Gilberto Mosconi, Marco Cardinali, Francesca Maradonna |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Sex Differentiation Molecular Sequence Data Physiology Biology Toxicology Sexual Behavior Animal Vitellogenins Vitellogenin chemistry.chemical_compound Phenols Fundulidae Internal medicine medicine Animals Sex Ratio Cloning Molecular Gonads Poecilia Base Sequence Reverse Transcriptase Polymerase Chain Reaction Reproduction biology.organism_classification Nonylphenol Blotting Southern Gonadosomatic Index Endocrinology Animals Newborn Gene Expression Regulation Sexual behavior chemistry Endocrine disruptor biology.protein RNA Female Sex ratio |
| Zdroj: | Reproductive Toxicology. 18:597-604 |
| ISSN: | 0890-6238 |
| Popis: | New born guppies, Poecilia reticulata, were exposed to a sublethal concentration of nonylphenol (NP) for 90 days, with the aim of evaluating the influence that this pollutant has on reproductive functions. At the end of treatment, the gender balance was significantly biased towards females (sex ratio = 0.3 males per female). Treated males displayed anomalous transcription of vitellogenin in correlation with a significant reduction of the gonadosomatic index (GSI); however, an increase of vitellogenin gene transcription, correlating directly with an increase in GSI, was observed in NP treated females. The hepatosomatic index (HSI) was significantly increased in exposed males and females. Females exposed to NP showed no alteration of sexual behavior or reproduction. These findings in guppies suggest that NP has estrogenic potency sufficient to disturb reproduction. Effects were transitory in nature because three months in uncontaminated water allowed males to recover normal sexual efficiency. |
| Databáze: | OpenAIRE |
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