Socio-cognitive functioning in stimulant polysubstance users

Autor: Katrin H. Preller, Lea M. Hulka, Oliver G. Bosch, Sara L. Kroll, Boris B. Quednow, Michael D. Wunderli, Markus R. Baumgartner, Matthias Vonmoos
Rok vydání: 2018
Předmět:
Zdroj: Drug and Alcohol Dependence. 190:94-103
ISSN: 0376-8716
DOI: 10.1016/j.drugalcdep.2018.06.001
Popis: Background: Using more than one psychotropic substance is accompanied by increased risks for psychiatric and physical disorders. Accordingly, deficits in basal cognitive functions have been consistently associated with polysubstance use (PSU), whereas little is known about potential impairments in more complex socio-cognitive skills, which are relevant for daily-life functioning. Therefore, we investigated the effects of toxicological validated stimulant PSU on social cognition under consideration of potential cumulative effects. Methods: We compared socio-cognitive performances of 47 individuals with stimulant PSU with 59 matched stimulant-naive controls using the Multifaceted Empathy Test (MET) and the Movie for the Assessment of Social Cognition (MASC). Additionally, social network size was assessed by the Social Network Questionnaire (SNQ). Hair and urine testing was employed to categorize three PSU subgroups (3, 4, and ≥5 substances used) and to ensure drug abstinence in controls. Results: Individuals with stimulant PSU showed lower emotional empathy (MET) and a smaller social network (SNQ) compared to controls (both with linear trends for increasing number of used substances: p
Databáze: OpenAIRE