Local epidermal growth factor delivery using nanopillared chitosan–gelatin films for melanogenesis and wound healing

Autor: Sevde Altuntas, Harkiranpreet Kaur Dhaliwal, Ahmed Eid Radwan, Mansoor Amiji, Fatih Buyukserin
Rok vydání: 2023
Předmět:
Zdroj: Biomaterials Science. 11:181-194
ISSN: 2047-4849
2047-4830
DOI: 10.1039/d2bm00836j
Popis: Epidermal growth factor (EGF) is required for various regulations of skin tissue including wound healing; however, it has limited stability due to the physicochemical conditions of the wound milieu. The lack of functional EGF within the wound can cause permanent tissue defects and therefore, current wound patch designs involve EGF-releasing components. Consequently, the focus of such systems is to improve the wound healing mechanism, with minimal attention on melanogenesis of the scar tissue. The present study investigates
Databáze: OpenAIRE