Horizontal and Vertical Transmission of West Nile Virus Genotype NY99 by Culex salinarius and Genotypes NY99 and WN02 by Culex tarsalis
| Autor: | John F. Anderson, Francis J. Ferrandino, Erol Fikrig, Andy J. Main, Gong Cheng |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Genotype West Nile virus viruses Culex tarsalis Biology medicine.disease_cause law.invention Mice law Virology Chlorocebus aethiops Disease Transmission Infectious medicine Animals Vero Cells virus diseases Articles Culex salinarius Infectious Disease Transmission Vertical Infection rate Animals Suckling Insect Vectors Culex Infectious Diseases Transmission (mechanics) Vector (epidemiology) Female Parasitology West Nile Fever Horizontal transmission |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 86:134-139 |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.2012.11-0473 |
| Popis: | Culex tarsalis is a superior horizontal and vertical vector of West Nile virus (WNV) compared with Culex salinarius. Culex salinarius transmitted WNV genotype NY99 (CT 2741-99 strain) horizontally to suckling mice at significantly lower rates than Cx. tarsalis on Days 8, 9, 10, and 12 post-infection, and Cx. salinarius transmitted WNV genotype NY99 to offspring at a lower vertical transmission infection rate than Cx. tarsalis. Culex tarsalis transmitted WNV genotypes NY99 and WN02 (CT S0084-08 strain) with equal efficiency. Daily percent horizontal transmission of genotype NY99 by Cx. tarsalis-infected per os and by intra-thoracic infection was not significantly different from daily transmission of genotype WN02 from Days 5–23 and Days 2–9 post-infection, respectively. Our findings do not support the previously published hypothesis that genotype NY99 was replaced in the New World by WN02 because of a shorter extrinsic incubation of WN02. |
| Databáze: | OpenAIRE |
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